KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
14.55
Human Site:
S2141
Identified Species:
24.62
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
S2141
E
D
A
L
P
K
H
S
F
V
N
H
Y
M
S
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
S2096
E
D
A
L
P
K
H
S
F
V
N
H
Y
M
S
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
I2045
L
H
Y
S
D
E
D
I
C
N
K
Y
N
G
A
Dog
Lupus familis
XP_547004
2144
235913
P2072
S
E
S
E
D
V
P
P
Q
H
S
F
V
N
H
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
K2121
D
Y
E
E
A
L
P
K
H
S
F
V
N
H
Y
Rat
Rattus norvegicus
XP_001073292
2181
239558
K2109
D
Y
E
E
A
L
P
K
H
S
F
V
N
H
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
Y2060
K
H
S
F
V
N
H
Y
M
S
D
P
T
Y
Y
Chicken
Gallus gallus
Q8AV58
2169
239459
S2093
E
D
E
L
P
K
H
S
F
V
N
H
Y
M
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
Y2055
K
H
S
F
V
N
H
Y
M
S
D
P
S
Y
F
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
S1206
K
R
T
A
S
Q
P
S
L
G
E
D
S
K
L
Fruit Fly
Dros. melanogaster
O97394
2224
246236
S2152
H
S
E
S
E
N
E
S
V
R
S
D
P
H
S
Honey Bee
Apis mellifera
XP_623565
2176
242722
S2088
S
S
V
T
E
K
P
S
E
I
S
S
T
D
S
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
D2158
L
S
A
L
V
G
R
D
I
R
S
Q
N
T
A
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
A2826
T
A
D
L
G
S
A
A
S
S
H
Y
A
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
100
0
0
N.A.
0
0
N.A.
6.6
93.3
N.A.
6.6
6.6
13.3
20
13.3
6.6
P-Site Similarity:
100
100
20
20
N.A.
6.6
6.6
N.A.
26.6
93.3
N.A.
26.6
20
20
33.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
22
8
15
0
8
8
0
0
0
0
8
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
15
22
8
0
15
0
8
8
0
0
15
15
0
8
0
% D
% Glu:
22
8
29
22
15
8
8
0
8
0
8
0
0
0
0
% E
% Phe:
0
0
0
15
0
0
0
0
22
0
15
8
0
0
8
% F
% Gly:
0
0
0
0
8
8
0
0
0
8
0
0
0
8
8
% G
% His:
8
22
0
0
0
0
36
0
15
8
8
22
0
22
8
% H
% Ile:
0
0
0
0
0
0
0
8
8
8
0
0
0
0
0
% I
% Lys:
22
0
0
0
0
29
0
15
0
0
8
0
0
15
0
% K
% Leu:
15
0
0
36
0
15
0
0
8
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
15
0
0
0
0
22
0
% M
% Asn:
0
0
0
0
0
22
0
0
0
8
22
0
29
8
0
% N
% Pro:
0
0
0
0
22
0
36
8
0
0
0
15
8
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% Q
% Arg:
0
8
0
0
0
0
8
0
0
15
0
0
0
0
0
% R
% Ser:
15
22
22
15
8
8
0
43
8
36
29
8
15
0
36
% S
% Thr:
8
0
8
8
0
0
0
0
0
0
0
0
15
8
0
% T
% Val:
0
0
8
0
22
8
0
0
8
22
0
15
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
8
0
0
0
0
15
0
0
0
15
22
15
22
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _